{"id":5283,"date":"2021-01-13T11:30:15","date_gmt":"2021-01-13T03:30:15","guid":{"rendered":"https:\/\/newsletter.cgust.edu.tw\/?p=5283"},"modified":"2021-01-13T11:39:27","modified_gmt":"2021-01-13T03:39:27","slug":"%e7%94%a2%e5%ad%b8%e5%90%88%e4%bd%9c%e6%8a%80%e8%a1%93%e7%a0%94%e7%99%bc%e7%b8%be%e5%84%aa%e7%8d%8e%e5%8b%b5%e7%8d%b2%e7%8d%8e%e6%95%99%e5%b8%ab%e7%99%bc%e8%a1%a8%e7%a0%94%e7%a9%b6%e5%8b%95%e6%85%8b-3","status":"publish","type":"post","link":"https:\/\/newsletter.cgust.edu.tw\/?p=5283","title":{"rendered":"\u7522\u5b78\u5408\u4f5c\u6280\u8853\u7814\u767c\u7e3e\u512a\u734e\u52f5\u7372\u734e\u6559\u5e2b\u767c\u8868\u7814\u7a76\u52d5\u614b\u5831\u5c0e \u65b0\u7a4e\u6db2\u614b\u767c\u9175\u8403\u53d6\u5c0f\u5206\u5b50\u7334\u982d\u7d20\u4e4b\u4fdd\u5065\u529f\u6548\u958b\u767c"},"content":{"rendered":"\n

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\"\"<\/figure>\n\n\n\n

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1.\u904e\u53bb\u90ed\u8001\u5e2b\u4e3b\u8981\u5f9e\u4e8b\u65bc\u5929\u7136\u7269\u6210\u4efd\u8403\u53d6\u8207\u958b\u767c\u6d3b\u6027\u6210\u5206\uff0c\u4e26\u7814\u7a76\u5176\u4fdd\u5065\u6a5f\u5236\u3002\u90ed\u8001\u5e2b2006\u5e74\u53d6\u5f97\u751f\u5316\u535a\u58eb\u5b78\u4f4d\u5f8c\uff0c2006-2008\uff0896\/3 ~ 97\/7\uff09\u6b77\u7d93\u570b\u5bb6\u885b\u751f\u7814\u7a76\u9662\u535a\u58eb\u5f8c\u7814\u7a76\u3001\u9ad8\u96c4\u9577\u5e9a\u91ab\u9662\u81e8\u5e8a\u57fa\u56e0\u9ad4\u66a8\u86cb\u767d\u8cea\u6838\u5fc3\u5be6\u9a57\u5ba4\u64d4\u4efb\u535a\u58eb\u7814\u7a76\u54e1\u30022015\uff08104\/8~\u81f3\u4eca\uff09\u4efb\u8077\u65bc\u672c\u6821\u5c08\u4efb\u6559\u6388\u3002\u7814\u7a76\u5ba4\uff1a\u529f\u80fd\u6027\u86cb\u767d\u8cea\u9ad4\u7814\u7a76\u5ba4\uff0c\u6210\u54e1\u67098\u4f4d\u5c08\u4efb\u78a9\u5b78\u58eb\u7d1a\u7814\u7a76\u52a9\u7406\u82071\u4f4d\u5927\u5b78\u5c08\u984c\u751f\u3002\u5be6\u9a57\u5ba4\u5f9e\u4e8b\uff0c\u86cb\u767d\u8cea\u8cea\u8b5c\u5206\u6790\u76f8\u95dc\u75be\u75c5\u4e4b\u7814\u7a76\uff0c\u8b93\u751f\u7269\u6a19\u5e5f(biomarkers)\u5f97\u4ee5\u5927\u898f\u6a21\u5206\u6790\uff0c\u4e26\u4e14\u85c9\u7531\u5206\u5b50\u751f\u7269\u7684\u57fa\u56e0\u8abf\u63a7\u5206\u6790\u751f\u7269\u6a19\u5e5f\u529f\u80fd\u6027(1-7)\u3002\u6b64\u5916\u958b\u767c\u5929\u7136\u7269\u8403\u53d6\u7269\u63d0\u4f9b\u8f14\u52a9\u6cbb\u7642\u7684\u53ef\u80fd\uff0c\u5f97\u4ee5\u9023\u7d50\u8f49\u8b6f\u91ab\u5b78(8-11)\u3002<\/p>\n\n\n\n

2.2011\u7d93\u7531\u672c\u6821\u7814\u7a76\u767c\u5c55\u8655\u7522\u5b78\u5408\u4f5c\u7d44\u7684\u5354\u52a9\u4e0b\uff0c\u90ed\u8001\u5e2b\u8207\u8461\u8404\u738b\u751f\u6280\u7814\u767c\u4e2d\u5fc3\u7c3d\u8a02\u7522\u5b78\u5408\u4f5c\u8a08\u756b\u6848(SCRPF6A0011)\uff0c\u9032\u884c\u958b\u767c\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u8403\u53d6\u7269\uff0c\u4e26\u63d0\u4f9b\u8f14\u52a9\u6cbb\u7642\u7684\u53ef\u80fd\u3002\u7522\u5b78\u8a08\u5283\u4e43\u5354\u52a9\u958b\u767c\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u767c\u9175\u6280\u8853\uff1b\u5229\u7528 Hericium erinaceus<\/em>\u83cc\u7d72\u9ad4\u767c\u9175\u7269\u3002\u7d93\u7531 HPLC\u5b9a\u6027\u5b9a\u91cf\u5206\u6790\u6709\u6548\u6210\u5206\u7334\u982d\u7d20A\uff0c\u8207 NMR\u5206\u6790\u51fa\u7d50\u69cb\uff0c\u8a72\u767c\u9175\u88fd\u7a0b\u53ef\u4ee5\u5f97\u5230\u5728\u6bcf\u516c\u65a4\u7334\u982d\u83c7\u985e\u83cc\u7d72\u9ad4\u51cd\u4e7e(Hericium erinaceus wet mycelium)\uff0c\u8403\u53d6\u6d3b\u6027\u6210\u5206\u7334\u982d\u7d20(Erinacine A\uff0c PubChem CID: 9867477)\u7d043-6 g\u3002<\/p>\n\n\n\n

3.\u4e4b\u5f8c\u9678\u7e8c\u901a\u904e\u79d1\u6280\u90e8\u7522\u5b78\u8a08\u5283\u4e4b\u88dc\u52a9\uff0c\u5f97\u4ee5\u958b\u767c\u529f\u80fd\u6027\u4fdd\u5065\u7522\u54c1\u3002\u7522\u5b98\u5b78\u5408\u4f5c\u6848 2011-\u81f3\u4eca\uff0c\u7334\u982d\u83c7\u7522\u54c1\u5ef6\u7de9\u8870\u8001\u529f\u80fd\u8a55\u4f30\u8a66(SCRPF6D0031)\u3001\u4ee5\u86cb\u767d\u8cea\u9ad4\u65b9\u6cd5\u958b\u767c\u7334\u982d\u83c7\u83cc\u7d72\u9ad4\u8403\u53d6\u7269\u5c0d\u5927\u9f20\u7f3a\u8840\u6027\u8166\u4e2d\u98a8\u7684\u4fdd\u8b77\u6a5f\u8f49\u4e4b\u6d3b\u6027\u7814\u7a76(NSC101-2622-B-255-001-CC3)\u3001\u8abf\u7bc0\u5167\u8cea\u7db2\u58d3\u529b\u8a0a\u865f\u5c0d\u5df4\u91d1\u68ee\u6c0f\u75c7\u52d5\u7269\u795e\u7d93\u5143\u58de\u6b7b\u53ca\u884c\u70ba\u7f3a\u9677\u4e4b\u4fdd\u8b77\u6a5f\u8f49\u4e4b\u7814\u7a76(103-2622-B-255-001-CC3)\u3001\u5c0d\u5be6\u9a57\u6027\u6cbb\u7642\u5927\u9f20\u5275\u50b7\u6027\u8166\u640d\u50b7\u4e4b\u7814\u7a76(108-2622-B-255-001-CC3)\u3002<\/p>\n\n\n\n

4.\u6211\u5011\u5229\u7528\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u51cd\u4e7e\u54c1(Hericium erinaceus<\/em> wet mycelia)\uff0c\u8207\u7d14\u5316\u8403\u53d6\u6d3b\u6027\u7269\u7334\u982d\u7d20\uff0c\u9032\u884c\u52d5\u7269\u5be6\u9a57\uff0c\u986f\u793a\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u51cd\u4e7e\u54c1\u7ba1\u9935\u98df\u3001\u7334\u982d\u7d20\u8179\u8154\u6ce8\u5c04\uff0c\u5747\u5c0d\u5927\u9f20\u8166\u4e2d\u98a8\u6897\u585e\u7f3a\u8840\u518d\u704c\u6ce8\u640d\u50b7\u4e4b\u4fdd\u8b77\u4f5c\u7528\u6709\u986f\u8457\u4e4b\u63d0\u5347(12)\u3002\u6709\u95dc\u7570\u5e38\u5167\u8cea\u7db2\u58d3\u529b\u8a0a\u865f\u76f8\u95dc\u9014\u5f91\u7814\u7a76\u5f88\u591a\uff0c\u5177\u6709\u8a31\u591a\u7684\u9776\u9ede\uff0c\u5c07\u6703\u7522\u751f\u8a31\u591a\u9632\u6cbb\u5e15\u91d1\u68ee\u75c5\u7684\u65b0\u624b\u6bb5\u3002\u9032\u4e00\u6b65\u5229\u7528\u7334\u982d\u83c7\u83cc\u7d72\u9ad4\u51cd\u4e7e\u54c1\u7ba1\u9935\u98df\u9032\u884c\u52d5\u7269\u5be6\u9a57\uff1b\u6839\u64da2005\u5e74\u7f8e\u570b\u98df\u54c1\u85e5\u7269\u7ba1\u7406\u5c40\u6240\u516c\u544a\u4e4b\u5be6\u9a57\u521d\u671f\u4f30\u7b97\u65b9\u6cd5(\u5c0f\u9f20\u9ad4\u91cd\u4ee3\u8b1d\u7387\u6bd4\u4f8b\u63a8\u4f30\u5176\u6210\u4eba\u4e00\u5929\u6240\u651d\u53d6\u91cf)\uff1aA.\u4f4e\u5291\u91cf\u7d44 (\u70ba3\u7c92\u81a0\u56ca\u5167\u5bb9\u7269)\uff1bB.\u4e2d\u5291\u91cf\u7d44(\u70ba6\u7c92\u81a0\u56ca\u5167\u5bb9\u7269)\uff1bC.\u9ad8\u5291\u91cf\u7d44(\u70ba12\u7c92\u81a0\u56ca\u5167\u5bb9\u7269)\u3002\u9810\u5148\u7ba1\u9935\u5c0f\u9f20\u7334\u982d\u83c7\u83cc\u7d72\u9ad430\u5929\uff0c\u5c0d\u65bc1-\u7532\u57fa-4-\u82ef\u57fa-1,2,3,6-\u56db\u6c2b\u5421\u5576(MPTP)\u6240\u8a98\u767c\u5c0f\u9f20\u591a\u5df4\u80fa\u795e\u7d93\u5143\u6bd2\u6027\u5177\u6709\u4fdd\u8b77\u4f5c\u7528\uff0c\u9019\u4e9b\u7d50\u679c\u986f\u793a\u964d\u4f4e\u5167\u8cea\u7db2\u58d3\u529b\u5f15\u8d77\u7684\u591a\u5df4\u80fa\u795e\u7d93\u5143\u640d\u5bb3(13)\u3002\u63a5\u7e8c\u518d\u8a55\u4f30\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u7334\u982d\u7d20A \u6cbb\u7642\u5e15\u91d1\u68ee\u6c0f\u75c7\u52d5\u7269\u6210\u6548\uff0c\u9023\u7e8c\u4e94\u5929\u6cbb\u7642\u8a55\u4f30\uff0c\u4e26\u63a2\u8a0e\u5167\u8cea\u7db2\u58d3\u529b\u8a0a\u865f\u5c0d\u8a98\u5c0e\u795e\u7d93\u5143\u751f\u9577\u5206\u5316\u7684\u6a5f\u5236\u3002\u986f\u793a\u56e0\u70ba\u7d66\u4e88\u8403\u53d6\u5c0f\u5206\u5b50\u7334\u982d\u7d20A \u7de9\u89e3 MPTP \u6240\u9020\u6210\u7684\u591a\u5df4\u80fa\u795e\u7d93\u7d30\u80de\u7684\u50b7\u5bb3\u6e1b\u4f4e\u3002\u6b64\u5916\u5728\u8166\u5207\u7247\u88e1\u7d0b\u72c0\u9ad4\u8207\u9ed1\u8cea\u5340\u7684\u591a\u5df4\u80fa\u795e\u7d93\u5143\uff0c\u7334\u982d\u7d20A(1.0 mg\/kg) i.p\uff0c\u9664\u4e86\u6291\u5236 MPP+\u6240\u8a98\u5c0e\u7684\u591a\u5df4\u80fa\u795e\u7d93\u7d30\u80de\u6b7b\u4ea1\uff0c\u8b49\u5be6\u8a98\u5c0ePAK1\/AKT\/LIMK2\/ERK\/Cofilin \u8a0a\u606f\u8def\u5f91\u591a\u5df4\u80fa\u795e\u7d93\u7d30\u80de\u751f\u9577\u53ef\u5851\u6027\u8def\u5f91\uff1b\u5be6\u9a57\u4e5f\u986f\u793a\u7334\u982d\u7d20A\u5c0d MPTP \u6bd2\u5bb3\u6240\u9020\u6210 N2a \u7684\u7d30\u80de\u51cb\u4ea1\u7684\u6709\u6548\u6e1b\u7de9\u4fdd\u8b77\u795e\u7d93\u7d30\u80de\uff0c\u662f\u900f\u904e\u963b\u65b7 IRE1a\/TRAF2,\u5167\u8cea\u7db2\u58d3\u529b\u8def\u5f91\u8207\u5404\u7a2e\u4e0b\u6e38\u8f49\u9304\u56e0\u5b50\u8207\u795e\u7d93\u6b7b\u4ea1\u86cb\u767d\u7684\u8868\u73fe (GADD45 and p21) (14)\u3002<\/p>\n\n\n\n

5.\u7d9c\u5408\u4ee5\u4e0a\u4e4b\u7814\u7a76\u3002\u6211\u5011\u958b\u767c\u7334\u982d\u83cc\u83cc\u7d72\u9ad4\u4fdd\u8b77\u8166\u795e\u7d93\u7d30\u80de\u767c\u708e\u6240\u626e\u6f14\u7684\u89d2\u8272\u76f8\u95dc\u6027\uff0c\u5728\u52d5\u8108\u7f3a\u8840\u8166\u4e2d\u98a8\u640d\u50b7\u3001\u5df4\u91d1\u68ee\u6c0f\u75c7\u6cbb\u7642\u6a5f\u5236\u7684\u5065\u5eb7\u7522\u54c1\u63d0\u4f9b\u7406\u8ad6\u57fa\u790e\u3002\u8461\u8404\u738b\u751f\u6280\u7814\u767c\u4e2d\u5fc3\u3010\u7334\u982d\u83c7\u83cc\u7d72\u9ad4\u9846\u7c92\u6d3b\u9038\u5eb7\u3011\u5df2\u65bc2015\/01\/15\u4e0a\u5e02\uff0c\u958b\u5275\u570b\u5167\u4fdd\u5065\u98df\u54c1\u751f\u6280\u3002\u53e6\u5916\uff0c2016\/07\/25\u61c9\u9080\u79d1\u6280\u90e8\u65b0\u8fb2\u696d\u751f\u6280\u7522\u5b78\u5a92\u5408\u6703\u4e4b\u91ab\u8fb2\u8de8\u9818\u57df\u7cfb\u5217\u767c\u8868\u6f14\u8b1b (15,16)\u3002<\/p>\n\n\n\n

6.\u4eca\u5e74\u8a08\u5283\u6848\uff0c\u5229\u7528 Hericium erinaceus<\/em>\u83cc\u7d72\u9ad4\u767c\u9175\u7269\uff0c\u9032\u968e\u7d14\u5316\u539f\u5275\u7334\u982d\u83c7\u985e\u83cc\u7d72\u9ad4\u6d3b\u6027\u7522\u7269\u7334\u982d\u7d20C (Erinacine C\uff0c PubChem CID: 15235994)\uff0c\u9019\u88fd\u7a0b\u518d\u7d93\u7531 HPLC\u5b9a\u6027\u5b9a\u91cf\u5206\u6790\uff0c NMR\u5206\u6790\u51fa\u7d50\u69cb\uff0c\u7d04\u53ef\u4ee5\u5f97\u5230\u6d3b\u6027\u6210\u5206\u7d042.0-3.0 g\uff1b\u6e96\u5099\u9032\u884c\u63a2\u8a0e\uff1a\u65b0\u7a4e\u6db2\u614b\u767c\u9175\u8403\u53d6\u5c0f\u5206\u5b50\u7334\u982d\u7d20\u6291\u5236\u8da8\u5316\u56e0 CCLs\/CXCLs\u6cbb\u7642\u795e\u7d93\u5143\u640d\u50b7\u4e4b\u529f\u80fd\u53ca\u5176\u6a5f\u5236\u7684\u76f8\u95dc\u6027\u6a5f\u5236\u7814\u7a76\u3002\u8a55\u4f30\u7334\u982d\u83cc\u7d20\u6210\u5206\uff0c\u53c3\u8207\u6291\u5236\u795e\u7d93\u7d30\u80de\u6027\u767c\u708e\u7684\u5168\u65b0\u6cbb\u7642\u9776\u6a19\u3002\u4f7f\u7528\u591a\u500b\u539f\u4ee3\u96e2\u9ad4\u795e\u7d93\u5143-\u795e\u7d93\u81a0\u8cea\u7d30\u80de\u57f9\u990a\u6a21\u5f0f\u4f86\u7814\u7a76 CCLs\/CXCLs\u5728\u7a0b\u5e8f\u6027\u795e\u7d93\u640d\u50b7\u4e2d\u7684\u529f\u80fd\u4f5c\u7528\u53ca\u5176\u6a5f\u5236<\/strong>\uff0c\u63d0\u4f9b\u7406\u8ad6\u57fa\u790e\u4ee5\u70ba\u6291\u5236\u6162\u6027\u795e\u7d93\u767c\u708e\u8f14\u52a9\u6cbb\u7642\u4e4b\u529f\u80fd\u6027\u958b\u767c\uff0c\u53ef\u671b\u9032\u4e00\u6b65\u62d3\u5c55\u83c7\u985e\u4fdd\u5065\u7522\u54c1\u3002<\/p>\n\n\n\n

  1. Kuo HC, Chang JC, Kuo HC<\/u><\/strong>, Yu HR, Wang CL, Lee CP, Huang LT, Yang KD. Identification of an Association Between Genomic Hypomethylation of FCGR2A and Susceptibility to Kawasaki Disease and Intravenous Immunoglobulin Resistance by DNA Methylation Array. Arthritis Rheumatol. 2015; 67:828-836. (2019 SCI Impact Factor 9.586)<\/li>
  2. Huang WS, Hsieh MC, Huang CY, Kuo YH, Tung SY, Shen CH, Hsieh YY, Teng CC, Lee KF, Chen TC, Lee KC, Kuo HC<\/u>*<\/sup><\/strong>. The Association of CXC Receptor 4 mediated signaling pathway with oxaliplatin-resistant human colorectal cancer cells. PLOS One. 2016; 11:e0159927. (2019 SCI Impact Factor 2.74)<\/li>
  3. Kuo HC<\/u><\/strong>\u2020<\/sup><\/strong>, Chang LC, Chen TC, Lee KC, Lee KF, Chen CN, Yu HR. Sterol Regulatory Element-Binding Protein-1c Regulates Inflammasome Activation in Gingival Fibroblasts Infected with High-Glucose-Treated Porphyromonas gingivalis. Front Cell Infect Microbiol. 2016; 6:195. (2019 SCI Impact Factor 4.123)<\/li>
  4. Huang YH\u2020<\/sup>, Kuo HC<\/u>\u2020<\/sup><\/strong>, Li SC, Cai XY, Liu SF, Kuo HC. HAMP promoter hypomethylation and increased hepcidin levels as biomarkers for Kawasaki disease. J Mol Cell Cardiol. 2018 ;117:82-87. \u2020<\/sup>Equally contributors. (2019 SCI Impact Factor 4.133)<\/li>
  5. Huang WS, Huang CY, Hsieh MC, Kuo YH, Tung SY, Shen CH, Hsieh YY, Teng CC, Lee KC, Lee KF, Kuo HC<\/u>*<\/sup><\/strong>. Expression of PRDX6 Correlates with Migration and Invasiveness of Colorectal Cancer Cells. Cell Physiol Biochem. 2018; 51: 2616-2630. (2017 SCI Impact Factor 5.5)<\/li>
  6. Yang YL, Kuo HC\u2020<\/sup><\/u><\/strong>, Wang FS, Huang YH. MicroRNA-29a Disrupts DNMT3b to Ameliorate Diet-Induced Non-Alcoholic Steatohepatitis in Mice. Int J Mol Sci. 2019; 20. pii: E1499. (2019 SCI Impact Factor 4.556)<\/li>
  7. Liu WS, Chen SY, Sheng HC, Lee MY, Kuo HC<\/u><\/strong>*<\/sup>. Investigation of Zn\/Sn ratio for improving the material quality of CZTS thin films with the reduction of Cu2-xS secondary phase. J. Alloy. Compd. 2021;853:157237. (2019 SCI Impact Factor<\/strong> 4.650).<\/li>
  8. Teng CC, Tung SY, Lee KC, Lee KF, Huang WS, Shen CH, Hsieh MC, Huang CY, Sheen JM, Kuo HC<\/u>*<\/sup><\/strong>. Novel regulator role of CIL-102 in epigenetic modifications of TNFR1\/TRAIL to induce cell apoptosis in human gastric cancer. Food Chem Toxicol . 2020 Nov 25;147:111856. doi: 10.1016\/j.fct.2020.111856.. (2019 SCI Impact Factor 4.679)<\/li>
  9. Lee KC, Lee KF, Tung SY, Huang WS, Lee LY, Chen WP, Chen CC, Teng CC, Shen CH, Hsieh MC, Kuo HC<\/u>*<\/sup><\/strong>. Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK\/p300\/p50 Signaling Pathway With Histone Acetylation. Front Pharmacol. (2019) 10:1174. (2019 SCI Impact Factor 4.225)<\/li>
  10. Tseng TH, Lin WL, Chang CK, Lee KC, Tung SY, Kuo HC<\/u>*<\/sup><\/strong>. Protective Effects of Morus Root Extract (MRE) Against Lipopolysaccharide-Activated RAW264.7 Cells and CCl4-Induced Mouse Hepatic Damage. Cell Physiol Biochem. 2018;51: 1376-1388. (2017 SCI Impact Factor 5.5)<\/li>
  11. Tseng TH, Lin WL, Chen ZH, Lee YJ, Shie MS, Lee KF, Shen CH, Kuo HC<\/u>*<\/sup><\/strong>. Moniliformediquinone as a potential therapeutic agent, inactivation of hepatic stellate cell and inhibition of liver fibrosis in vivo. J Transl Med. 2016; 14:263. (2019 SCI Impact Factor 4.124)<\/li>
  12. Lee KF, Chen JH, Teng CC, Shen CH, Hsieh MC, Lu CC, Lee KC, Lee LY, Chen WP, Chen CC, Huang WS, Kuo HC*<\/u>. <\/strong>Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS\/p38 MAPK and Nitrotyrosine. Int. J. Mol. Sci. 15 (2014), 15073-15089. (2019 SCI Impact Factor 4.556)<\/li>
  13. Kuo HC<\/u><\/strong>\u2020<\/sup><\/strong>, Lu CC, Shen CH, Tung SY, Hsieh MC, Lee KC, Lee LY, Chen CC, Teng CC, Huang WS, Chen TE, Lee KF. Hericium erinaceus mycelium and its isolated erinacine A protection from MPTP-induced neurotoxicity through the ER stress, triggering an apoptosis cascade. J Transl Med. 2016; 14:78. (2019 SCI Impact Factor 4.124)<\/li>
  14. Lee KF, Tung SY, Teng CC, Shen CH, Hsieh MC, Huang CY, Lee KC, Lee LY, Chen WP, Chen CC, Huang WS, Kuo HC<\/u>*<\/sup><\/strong>. Post-Treatment With Erinacine A, a Derived Diterpenoid of H. erinaceus, Attenuates Neurotoxicity in MPTP Model of Parkinson’s Disease. Antioxidants (Basel). 2020; 9:137. (2019 SCI Impact Factor 5.014)<\/li>
  15. https:\/\/www.youtube.com\/watch?v=h-s95qlioFg&feature=youtu.be<\/li>
  16. https:\/\/www.youtube.com\/watch?v=TfdPJFvaASw&feature=youtu.be<\/li><\/ol>\n\n\n\n
    \"\"<\/figure>\n\n\n\n

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